Atypical fibroxanthoma of the skin with metastasis

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Atypical Fibroxanthoma

Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. AFX is characterized by its association with ultraviolet radiation, not only from a clinical aspect, but also from a molecular aspect. Making a diagnosis of AFX is challenging, and it is important to differentiate it from squamous ce...

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Atypical Fibroxanthoma of the Eyelid

Atypical fibroxanthoma (AFX) is an uncommon, fibrohistiocytic tumor of the skin that occurs due to actinic damage in the elderly (1). AFX rarely affects eyelid (2). It appears as solitary nodule that smaller than 2 cm (3). Boynton was the first to describe a case of AFX involving the eyelid in the literature (2). Aggresive recurrence was reported in few AFX cases, despite the benign nature of t...

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Atypical fibroxanthoma†

Atypical fibroxanthoma (AFX) is a rare skin neoplasm of low-grade malignancy and fibroblastic origin. AFX is a curable cutaneous disease and the diagnosis depends on knowledge of its clinical and histological features and combined immunohistochemistry markers. This study presents a case of a male patient, aged 90 years, presented with painless skin lesion in his ear. The lesion had been growing...

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Atypical fibroxanthoma with lymphomatoid reaction.

BACKGROUND Atypical fibroxanthoma (AFX) represents an uncommon skin tumor typically occurring on sun-damaged skin of the elderly. Histopathologic variants include spindled, clear cell, osteoid, osteoclastic, chondroid, pigmented, granular cell and myxoid lesions. To date, an atypical lymphoid infiltrate, including CD30-positive large cells mimicking lymphomatoid papulosis, has not been describe...

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Atypical fibroxanthoma of the auricle.

occasionally xanthomized, with marked nuclear pleomorphism, prominent nucleoli and atypical mitoses (Fig. 2), together with multinucleated giant cells. Immunohistochemistry revealed positivity for vimentin (Fig. 3A), actin, CD68, CD99 and CD10, while results for S100, HMB45, CD34, desmin, caldesmon and cytokeratins AE1/AE3 and 20 (Fig. 3B) were negative, confirming that it was an atypical fibro...

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ژورنال

عنوان ژورنال: Cancer

سال: 1986

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(19860115)57:2<368::aid-cncr2820570230>3.0.co;2-n